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Show HN: Localscope–Limit scope of Python functions for reproducible execution

uv overtakes Poetry (for Wagtail users)

ASK HN: How to engineer a JavaScript to Python migration?

Show HN: Aiopandas – Async .apply() and .map() for Pandas, Faster API/LLMs Calls

Show HN: Online Python Compiler with Libraries

Switching from Pyenv to Uv

Fastplotlib: Driving scientific discovery through data visualization

Performance of the Python 3.14 tail-call interpreter

Python Workers Redux: Wasm Snapshots and Native uv Tooling

Cloudflare's latest advancements in Python Workers revolutionize serverless performance with near-instant cold starts, expanded package compatibility, and streamlined workflows via the uv package manager. By leveraging memory snapshots and WebAssembly, Cloudflare drastically reduces startup times, making Python a prime choice for AI and data science applications. By Steef-Jan Wiggers

Google Metrax Brings Predefined Model Evaluation Metrics to JAX

Recently open-sourced by Google, Metrax is a JAX library providing standardized, performant metrics implementations for classification, regression, NLP, vision, and audio models. By Sergio De Simone

[P] A memory effecient TF-IDF project in Python to vectorize datasets large than RAM

My Python farming game has helped lots of people learn how to program! As a solo dev, seeing this is so wholesome.

My Python farming game has helped lots of people learn how to program! As a solo dev, seeing this is so wholesome.

MI6 (British Intelligence equivalent to the CIA) will be requiring new agents to learn how to code in Python. Not only that, but they're widely publicizing it.

ty, a fast Python type checker by the uv devs, is now in beta

Valhalla? Python? Withers? Lombok? - Ask the Architects at JavaOne'25

Sick of uploading sensitive PDFs to ChatGPT? I built a fully offline "Second Brain" using Llama 3 + Python (No API keys needed)

Deprecations via warnings don’t work for Python libraries

Most used programming languages in 2025

pathwaycom

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pathway

Python ETL framework for stream processing, real-time analytics, LLM pipelines, and RAG.

yt-dlp

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yt-dlp

A feature-rich command-line audio/video downloader

vwxyzjn

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cleanrl

High-quality single file implementation of Deep Reinforcement Learning algorithms with research-friendly features (PPO, DQN, C51, DDPG, TD3, SAC, PPG)

frappe

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hrms

Open Source HR and Payroll Software

donnemartin

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system-design-primer

Learn how to design large-scale systems. Prep for the system design interview. Includes Anki flashcards.

ranaroussi

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yfinance

Download market data from Yahoo! Finance's API

sympy

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sympy

A computer algebra system written in pure Python

9001

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copyparty

Portable file server with accelerated resumable uploads, dedup, WebDAV, FTP, TFTP, zeroconf, media indexer, thumbnails++ all in one file, no deps

AUTOMATIC1111

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stable-diffusion-webui

Stable Diffusion web UI