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Clinical genetics and the problem of uncertain significance

A single lock of hair could rewrite what we know about Inca record-keeping

GPT-4o quoted deleted GPT-5 content. Model isolation appears brok

Living with Williams Syndrome, the 'opposite of autism' (2014)

Hyundai wants loniq 5 customers to pay for cybersecurity patch in baffling move

Running Wayland Clients as Non-Root Users on Yocto

Why Love Matters Most

Simulator of the life of a 30-year-old in the UK

Show HN: unsafehttp – tiny web server from scratch in C, running on an orange pi

Meta spends more guarding Mark Zuckerberg than Apple, Nvidia, Microsoft, Amazon, and Alphabet do for their own CEOs—combined

Tiny proteins in ‘junk’ DNA promise next obesity drug breakthrough | Using gene-editing tech, researchers have identified "junk" proteins that could lead to next-gen obesity drugs

Added Qwen 0.6B to the small model overview in IFEval.

[D] model architecture or data?

The “record once, forget forever” hack I’ve been testing

What does it feel like: Cloud LLM vs Local LLM.

Replaced a $45k Content Team with a $20/mo AI System We Command From Slack.

Russia restricts WhatsApp and Telegram features after refusal to hand over user data | The apps are accused of aiding fraud and terrorism

[D] Cool new ways to mix linear optimization with GNNs? (LP layers, simplex-like updates, etc.)

Z.ai

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GLM-4.5V

Task: image-text-to-text

OpenAI

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gpt-oss-20b

Task: text-generation

OpenAI

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gpt-oss-120b

Task: text-generation

Tencent

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Hunyuan-GameCraft-1.0

Task: image-to-video

Google

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gemma-3-270m

Task: text-generation

Qwen

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Qwen-Image

Jan

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Jan-v1-4B

Task: text-generation

Google

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gemma-3-270m-it

Task: text-generation

rednote-hilab

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dots.ocr

Task: image-text-to-text